Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 36 Reviews
8.6
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
Read More
Most Useful Reviews
9.5
No constipation noted
This is the best iron! I battled anaemia and dizziness for ages and suffered from severe constipation with other medications. A doctor recommended this easily digestible iron from Solgar, which has been my salvation! No side effects or constipation, just one capsule daily with food. Within a month, my hemoglobin rose above average and my ferritin improved as well. I continue to take it.
Read More
9.5
Great absorption noted
This is a great iron supplement! It’s in a good absorbable chelated form which rarely causes side effects. Although my deficit isn’t large, it did help. I added vitamin C for better absorption and took it after meals. I experienced no constipation and just observed a change in stool colour. After eight weeks, my ferritin and hemoglobin levels improved.
Read More
9.5
No nausea experienced
Nausea-free iron supplement. When I was examined at the hospital, my ferritin was 12 and I suffered from severe iron deficiency. I purchased an iron supplement but vomited immediately after taking it. Other iron supplements caused rough stomach and severe nausea, but this one is the only one I can take without feeling sick. I consumed about half the bottle with no side effects. While chelated iron has a risk of cancer, this non-chelated iron can be taken safely.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
Read More
User Reviews
USERS' SCORE
Good
Based on 36 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
No constipation noted
This is the best iron! I battled anaemia and dizziness for ages and suffered from severe constipation with other medications. A doctor recommended this easily digestible iron from Solgar, which has been my salvation! No side effects or constipation, just one capsule daily with food. Within a month, my hemoglobin rose above average and my ferritin improved as well. I continue to take it.
Read More
9.5
Great absorption noted
This is a great iron supplement! It’s in a good absorbable chelated form which rarely causes side effects. Although my deficit isn’t large, it did help. I added vitamin C for better absorption and took it after meals. I experienced no constipation and just observed a change in stool colour. After eight weeks, my ferritin and hemoglobin levels improved.
Read More
9.5
No nausea experienced
Nausea-free iron supplement. When I was examined at the hospital, my ferritin was 12 and I suffered from severe iron deficiency. I purchased an iron supplement but vomited immediately after taking it. Other iron supplements caused rough stomach and severe nausea, but this one is the only one I can take without feeling sick. I consumed about half the bottle with no side effects. While chelated iron has a risk of cancer, this non-chelated iron can be taken safely.
Read More
9.5
Stopped hair loss
The best!!! Rapidly replenished my iron deficiency and increased ferritin. After COVID, my hair fell out badly, resulting in noticeable bald patches. I checked my levels – ferritin was at 18, low B12, and high homocysteine. I took various supplements including Vitamin C with meals, and introduced iron after 1.5 months, which boosted ferritin from 18 to 63 over 49 days. I also made dietary changes, adding iron-rich foods. After several months, with my levels rising, my hair loss ceased. Always remember to take iron with an acidic drink for better absorption!
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9
Effective in raising ferritin
This supplement increased my ferritin from 15 to 37 µg/l and iron levels from 16 to 21 µmol/l within two months. I took two capsules daily with food, consistently using vitamin C to enhance absorption, though I couldn't tolerate higher doses. I’m extremely satisfied with the results compared to a previous pharmacy version that only improved ferritin by one unit.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Bereswill S, Mousavi S, Weschka D, Buczkowski A, Schmidt S, et al. Iron Deprivation by Oral Deferoxamine Application Alleviates Acute Campylobacteriosis in a Clinical Murine Infection Model. Biomolecules. 2022;13. doi:10.3390/biom13010071
